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In people with non-dialysis-dependent CKD and ischemic heart disease, does coronary revascularization (PCI or CABG) plus medical therapy, compared with medical therapy alone, reduce death, cardiovascular events or kidney harms in randomized trials?

DoneStarted Oct 29, 2026, 10:07 UTCFinished Oct 29, 2026, 10:12 UTCVersion 3

Stages

  1. Finding the known studies(done)
  2. Drafting(done)
  3. Checking MeSH(done)
  4. Counting in PubMed(done)
  5. Checking known studies(done)
  6. Comparing with the reference(done)
  7. Run Search(done)
  8. Saving(done)
Run log (27)
  1. Finding the known studies: Finding 8 known studies in PubMed
  2. Drafting: Drafting concepts and terms
  3. Checking MeSH: Checking every MeSH heading, Supplementary Concept and publication type against NLM
  4. Counting in PubMed: Running 18 lines on PubMed
  5. Line 4: 503,270 records
  6. Line 3: 504,795 records
  7. Line 1: 209,392 records
  8. Line 5: 519,062 records
  9. Line 6: 697,830 records
  10. Line 7: 131,943 records
  11. Line 9: 298,517 records
  12. Line 10: 528,120 records
  13. Line 11: 2,780,289 records
  14. Line 2: 415,812 records
  15. Line 12: 2,982,529 records
  16. Line 15: 1,039 records
  17. Line 8: 263,478 records
  18. Line 14: 14,004,986 records
  19. Line 16: 643,741 records
  20. Line 17: 2,288,809 records
  21. Line 18: 2,640,713 records
  22. Line 13: 1,380 records
  23. Checking known studies: Checking which known studies the final query finds
  24. Comparing with the reference: Comparing with the reference strategy
  25. Run Search: Fetching the first 20 records
  26. Saving: Saving the run
  27. Finished.

Final count (line 15)

1,039

Open in PubMed (opens in a new tab)
Query as run (1,964 characters)((("Renal Insufficiency, Chronic"[Mesh] OR "Renal Insufficiency"[Mesh:NoExp] OR "Glomerular Filtration Rate"[Mesh]) OR ("chronic kidney disease*"[tiab] OR CKD[tiab] OR "chronic renal failure"[tiab] OR "chronic kidney failure"[tiab] OR "chronic renal disease"[tiab] OR "renal insufficiency"[tiab] OR "kidney insufficiency"[tiab] OR "renal impairment"[tiab] OR "kidney impairment"[tiab] OR "renal dysfunction"[tiab] OR "kidney dysfunction"[tiab] OR "glomerular filtration rate"[tiab] OR eGFR[tiab] OR "creatinine clearance"[tiab] OR "kidney function"[tiab] OR "renal function"[tiab])) AND (("Myocardial Ischemia"[Mesh]) OR ("coronary artery disease*"[tiab] OR "coronary disease*"[tiab] OR "coronary heart disease*"[tiab] OR "ischemic heart disease"[tiab] OR "ischaemic heart disease"[tiab] OR "myocardial ischemia"[tiab] OR "myocardial ischaemia"[tiab] OR "myocardial infarction"[tiab] OR angina[tiab] OR "acute coronary syndrome*"[tiab] OR "coronary stenosis"[tiab] OR "coronary occlusion"[tiab] OR "multivessel coronary"[tiab] OR NSTEMI[tiab] OR STEMI[tiab])) AND (("Myocardial Revascularization"[Mesh] OR "Percutaneous Coronary Intervention"[Mesh] OR "Coronary Artery Bypass"[Mesh]) OR (revasculari*[tiab] OR "percutaneous coronary intervention*"[tiab] OR PCI[tiab] OR "coronary angioplasty"[tiab] OR "coronary stent*"[tiab] OR stenting[tiab] OR "coronary artery bypass"[tiab] OR CABG[tiab] OR "bypass surgery"[tiab] OR "invasive strateg*"[tiab] OR "invasive management"[tiab] OR "invasive treatment"[tiab] OR "invasive approach"[tiab])) AND (("Randomized Controlled Trials as Topic"[Mesh] OR "Clinical Trials as Topic"[Mesh] OR "Random Allocation"[Mesh]) OR (random*[tiab] OR trial*[tiab] OR "post hoc"[tiab] OR "ISCHEMIA-CKD"[tiab]))) NOT ("Comment"[Publication Type] OR "Editorial"[Publication Type] OR "Letter"[Publication Type] OR "Case Reports"[Publication Type] OR "Preprint"[Publication Type] OR "Review"[Publication Type] OR (animals[mh] NOT humans[mh]))

Known studies

5 of 6 found

95% CI 36%–100%

Only studies the model never saw are counted. Finding known studies does not prove the search is complete.

Each study (8)
  • Found: 32386761PMID 32386761 · held back for validation
  • Found: 22728005PMID 22728005 · shown to the model
  • Found: 19464462PMID 19464462 · held back for validation
  • Found: 30590726PMID 30590726 · held back for validation
  • Found: 19962469PMID 19962469 · held back for validation
  • Found: 24011740PMID 24011740 · shown to the model
  • Found: 17161052PMID 17161052 · held back for validation
  • Missed: 19423566PMID 19423566 · held back for validation · removed by the exclusions or limits

Reference strategy

18%

relative recall: 204 of the reference's 1,107 records

Relative recall counts every record the reference finds, relevant or not, so it does not show how many relevant studies this search finds.

This search finds 1,039 records in total. The reference was run as its final line.

Search lines

Vocabulary terms are marked ✓︎ valid, ↪︎ mapped to the preferred heading, ✗︎ not found, ⚠︎ not checked.
Numbered search lines with their PubMed counts
No.SearchResults
1

Chronic kidney disease / renal impairment

"Renal Insufficiency, Chronic"[Mesh] (MeSH heading valid: D051436) OR "Renal Insufficiency"[Mesh:NoExp] (MeSH heading valid: D051437) OR "Glomerular Filtration Rate"[Mesh] (MeSH heading valid: D005919)		209,392
2

Chronic kidney disease / renal impairment

"chronic kidney disease*"[tiab] OR CKD[tiab] OR "chronic renal failure"[tiab] OR "chronic kidney failure"[tiab] OR "chronic renal disease"[tiab] OR "renal insufficiency"[tiab] OR "kidney insufficiency"[tiab] OR "renal impairment"[tiab] OR "kidney impairment"[tiab] OR "renal dysfunction"[tiab] OR "kidney dysfunction"[tiab] OR "glomerular filtration rate"[tiab] OR eGFR[tiab] OR "creatinine clearance"[tiab] OR "kidney function"[tiab] OR "renal function"[tiab]		415,812
3

Chronic kidney disease / renal impairment · block

1 OR 2		504,795
4

Ischemic heart disease

"Myocardial Ischemia"[Mesh] (MeSH heading valid: D017202)		503,270
5

Ischemic heart disease

"coronary artery disease*"[tiab] OR "coronary disease*"[tiab] OR "coronary heart disease*"[tiab] OR "ischemic heart disease"[tiab] OR "ischaemic heart disease"[tiab] OR "myocardial ischemia"[tiab] OR "myocardial ischaemia"[tiab] OR "myocardial infarction"[tiab] OR angina[tiab] OR "acute coronary syndrome*"[tiab] OR "coronary stenosis"[tiab] OR "coronary occlusion"[tiab] OR "multivessel coronary"[tiab] OR NSTEMI[tiab] OR STEMI[tiab]		519,062
6

Ischemic heart disease · block

4 OR 5		697,830
7

Coronary revascularization (PCI or CABG)

"Myocardial Revascularization"[Mesh] (MeSH heading valid: D009204) OR "Percutaneous Coronary Intervention"[Mesh] (MeSH heading valid: D062645) OR "Coronary Artery Bypass"[Mesh] (MeSH heading valid: D001026)		131,943
8

Coronary revascularization (PCI or CABG)

revasculari*[tiab] OR "percutaneous coronary intervention*"[tiab] OR PCI[tiab] OR "coronary angioplasty"[tiab] OR "coronary stent*"[tiab] OR stenting[tiab] OR "coronary artery bypass"[tiab] OR CABG[tiab] OR "bypass surgery"[tiab] OR "invasive strateg*"[tiab] OR "invasive management"[tiab] OR "invasive treatment"[tiab] OR "invasive approach"[tiab]		263,478
9

Coronary revascularization (PCI or CABG) · block

7 OR 8		298,517
10

Randomized trials

"Randomized Controlled Trials as Topic"[Mesh] (MeSH heading valid: D016032) OR "Clinical Trials as Topic"[Mesh] (MeSH heading valid: D002986) OR "Random Allocation"[Mesh] (MeSH heading valid: D011897)		528,120
11

Randomized trials

random*[tiab] OR trial*[tiab] OR "post hoc"[tiab] OR "ISCHEMIA-CKD"[tiab]		2,780,289
12

Randomized trials · block

10 OR 11		2,982,529
13

combined

3 AND 6 AND 9 AND 12		1,380
14

excluded

"Comment"[Publication Type] (publication type valid: D016420) OR "Editorial"[Publication Type] (publication type valid: D016421) OR "Letter"[Publication Type] (publication type valid: D016422) OR "Case Reports"[Publication Type] (publication type valid: D002363) OR "Preprint"[Publication Type] (publication type valid: D000076942) OR "Review"[Publication Type] (publication type valid: D016454) OR (animals[mh] NOT humans[mh])		14,004,986
15Final

exclusions removed

13 NOT 14		1,039
16

Death, cardiovascular events and kidney harms

"Mortality"[Mesh] (MeSH heading valid: D009026) OR "Acute Kidney Injury"[Mesh] (MeSH heading valid: D058186) OR "Renal Dialysis"[Mesh] (MeSH heading valid: D006435)		643,741
17

Death, cardiovascular events and kidney harms

mortality[tiab] OR death*[tiab] OR "major adverse cardiac event*"[tiab] OR MACE[tiab] OR "contrast induced nephropathy"[tiab] OR "acute kidney injury"[tiab] OR "kidney failure"[tiab]		2,288,809
18

Death, cardiovascular events and kidney harms · block

16 OR 17		2,640,713

Issues

0 errors, 1 warnings, 0 notes
  • Warning: Publication types excluded with NOT (Comment, Editorial, Letter, Case Reports, Preprint, Review): report and justify the exclusion.

First records

The first 20 of the final line's records, as PubMed sorts them.
  1. High-Potency P2Y12 Inhibitors Among Patients With Chronic Coronary Syndrome Undergoing PCI: An Analysis From the NCDR CathPCI Registry. (PubMed, opens in a new tab)

    Fath AR, Rymer J, Marks A et al. · Circulation. Cardiovascular interventions · 2026 · PMID 42861503

  2. Effect of a single high-concentration sodium bicarbonate bolus on contrast-induced nephropathy in STEMI patients undergoing Primary PCI: a prospective randomized study. (PubMed, opens in a new tab)

    Zahid B, Bendary A, AbdelHay M et al. · Acta cardiologica · 2026 · PMID 42858262

  3. Inflammation, Infarct Size and 10-Year Mortality in STEMI Patients Stratified by the ORBI Risk Score: A DANAMI-3 Sub-study. (PubMed, opens in a new tab)

    Kunkel JB, Lønborg J, Frydland M et al. · European heart journal. Acute cardiovascular care · 2026 · PMID 42828419

  4. Liver Disease, Liver Fibrosis, and the Invasive-Management Gap in Acute Myocardial Infarction: A Single-Center Cohort with Dual ICD and FIB-4 Stratification. (PubMed, opens in a new tab)

    Pradeep AG, Butt MA, Jia K et al. · Journal of cardiovascular development and disease · 2026 · PMID 42783015

  5. Impact of Renal Dysfunction on FFR- or IVUS-Guided PCI for Intermediate Coronary Stenosis. (PubMed, opens in a new tab)

    He W, Tang W, Zhang J et al. · JACC. Asia · 2026 · PMID 42762209

  6. Influence of Chronic Kidney Disease on Outcomes After Paclitaxel-Coated Balloon Angioplasty for Coronary In-Stent Restenosis. (PubMed, opens in a new tab)

    Tehrani BN, Vavilin I, Shlofmitz R et al. · Circulation. Cardiovascular interventions · 2026 · PMID 42751771

  7. The Ischemia-Plaque Paradox: A Mechanistic Framework for Chronic Coronary Syndromes. (PubMed, opens in a new tab)

    Klein LW · Cardiology in review · 2026 · PMID 42745232

  8. Atherosclerotic Cardiovascular Disease in CKD: Contemporary Insights into Pathogenesis, Diagnosis, and Management. (PubMed, opens in a new tab)

    Correa S, Cunningham JW, Mc Causland FR · Clinical journal of the American Society of Nephrology : CJASN · 2026 · PMID 42735033

  9. Protective Effect of Sodium-Glucose Cotransporter 2 Inhibitors (SGLT2i) on Liver Function: Results From MELD Analysis in Surgical Revascularization-A Preliminary Study. (PubMed, opens in a new tab)

    Urbanowicz T, Bajsert M, Kowalczyk MŁ et al. · Medical science monitor : international medical journal of experimental and clinical research · 2026 · PMID 42732086

  10. Timing of non-culprit revascularization in STEMI with multivessel disease: A contemporary meta-analysis of immediate and staged strategies. (PubMed, opens in a new tab)

    Ali R, Naeem M, Harrisingh K et al. · Cardiovascular revascularization medicine : including molecular interventions · 2026 · PMID 42649013

  11. Glucagon-Like Peptide 1 Receptor Agonists, Mortality, and Cardiovascular Outcomes in Serious Mental Illness. (PubMed, opens in a new tab)

    McIntyre RS, Zhang-James Y, Kwan ATH · JAMA psychiatry · 2026 · PMID 42647034

  12. Development and Preliminary Assessment of a Mortality Risk Score in Patients with Coronary Artery Disease Receiving Dual Antiplatelet Therapy After Percutaneous Coronary Intervention. (PubMed, opens in a new tab)

    Nurmukhammad F, Zhangelova S, Sugraliyev A et al. · Clinics and practice · 2026 · PMID 42645145

  13. [Development and validation of a prediction score for gastrointestinal bleeding following percutaneous coronary intervention in East Asian patients with acute coronary syndrome]. (PubMed, opens in a new tab)

    Zheng W, Gong ZT, Li X et al. · Zhonghua xin xue guan bing za zhi · 2026 · PMID 42595519

  14. Clinical Outcomes of Intravascular Lithotripsy for Severely Calcified Coronary Lesions: A Single-Center Study. (PubMed, opens in a new tab)

    Huang CP, Tsao TP, Fu HN et al. · Acta Cardiologica Sinica · 2026 · PMID 42524114

  15. One-Year Outcomes of High-Risk Percutaneous Coronary Interventions With Versus Without Mechanical Circulatory Support: Propensity Score-Matched Analysis. (PubMed, opens in a new tab)

    Gąsecka A, Pietrasik A, Pawłowski T et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026 · PMID 42516021

  16. ACEF score and its predictive performance in coronary artery disease patients undergoing PCI: a systematic review and meta-analysis of the C-statistic. (PubMed, opens in a new tab)

    Rasti SD, Fagi RA, Arvianti MZ et al. · AsiaIntervention · 2026 · PMID 42500622

  17. Machine Learning Analysis of Sex Differences in Cardiovascular-Kidney-Metabolic Risk Factors and Prognosis Among Patients With Moderate-to-Severe Coronary Artery Calcification: Prospective Cohort Study. (PubMed, opens in a new tab)

    Ye Z, Xie E, Lin Z et al. · Journal of medical Internet research · 2026 · PMID 42462211

  18. Impact of below-the-knee runoff in patients undergoing drug-coated balloon angioplasty for femoropopliteal disease: a propensity score-matched analysis. (PubMed, opens in a new tab)

    Li C, Zhu Y, Yang W et al. · BMC cardiovascular disorders · 2026 · PMID 42420851

  19. Effect of remote ischemic preconditioning on the risk of contrast-induced acute kidney injury in patients with coronary heart disease undergoing percutaneous coronary intervention. (PubMed, opens in a new tab)

    Wu Y, Zhang X, Liu P · Frontiers in cardiovascular medicine · 2026 · PMID 42368850

  20. A score system to determine the 5-year survival in patients with asymptomatic carotid stenosis under best medical therapy: Results from the Carotid Asymptomatic Stenosis study. (PubMed, opens in a new tab)

    Lodato M, Pini R, Rocchi C et al. · Journal of vascular surgery · 2026 · PMID 42285186

Export

Strategy (.txt)PMIDs (.txt)MEDLINE (.txt)Provenance (.json)

The strategy file has the numbered lines with counts, the search date and the AI-use statement. PMIDs and MEDLINE are fetched from PubMed when you download, so they reflect PubMed today.

Checking PubMed for the current list of PMIDs…

Objective and notes from the draft

To assess whether coronary revascularization (PCI or CABG) plus medical therapy, compared with medical therapy alone, reduces death, cardiovascular events or kidney harms in people with non-dialysis-dependent chronic kidney disease and ischemic heart disease, as shown in randomized trials and their subgroup or post hoc analyses.

  • The restriction to non-dialysis-dependent CKD cannot be searched reliably, because subgroup analyses rarely state dialysis status in indexing; dialysis patients must be excluded at screening.
  • Randomized design is searched sensitively (randomization, trial, post hoc, trial headings) rather than with the Randomized Controlled Trial publication type, so that CKD subgroup and post hoc analyses indexed as cohort or retrospective studies, such as PMID 22728005, are not lost.
  • The outcome block is optional and not combined: the question's outcomes (death, cardiovascular events, kidney harms) are reported in nearly all relevant trials and adding them would lower sensitivity.
  • Optimal medical therapy is not searched, as the comparator is implied by trials of revascularization versus medical therapy.
  • CAD is not used as an abbreviation because it also means computer-aided design or detection.
  • The renal impairment block includes eGFR and renal function phrases so that trials reporting results by kidney function strata are found; this adds some noise that screening must remove.

Edit the strategy

Changes are not searched until you recount. Each recount is saved as a new version.

Chronic kidney disease / renal impairmentPopulation

504,795 records · 19 of 19 terms on · 2 suggestions off

  • MeSH valid: D051436AI

    "Renal Insufficiency, Chronic"[Mesh]

    Main heading for chronic kidney disease, used for the CKD analysis of COURAGE (PMID 24011740).

  • MeSH valid: D051437AI

    "Renal Insufficiency"[Mesh:NoExp]

    Broader heading used for renal impairment subgroups, as in the OAT analysis (PMID 22728005); not exploded to keep out acute kidney injury.

  • MeSH valid: D005919AI

    "Glomerular Filtration Rate"[Mesh]

    Trials often define CKD subgroups only by eGFR, as in PMID 22728005.

  • TextAI

    "chronic kidney disease*"[tiab]

    Standard name for the population, often mentioned only in the abstract of subgroup analyses.

    Fields to search for chronic kidney disease
  • TextAI

    CKD[tiab]

    Common, specific abbreviation for chronic kidney disease.

    Fields to search for CKD
  • TextAI

    "chronic renal failure"[tiab]

    Older entry-term synonym for chronic kidney disease.

    Fields to search for chronic renal failure
  • TextAI

    "chronic kidney failure"[tiab]

    Variant wording of chronic kidney disease.

    Fields to search for chronic kidney failure
  • TextAI

    "chronic renal disease"[tiab]

    Variant wording of chronic kidney disease.

    Fields to search for chronic renal disease
  • TextAI

    "renal insufficiency"[tiab]

    Entry-term wording, also covers chronic renal insufficiency.

    Fields to search for renal insufficiency
  • TextAI

    "kidney insufficiency"[tiab]

    Entry-term wording, also covers chronic kidney insufficiency.

    Fields to search for kidney insufficiency
  • TextAI

    "renal impairment"[tiab]

    Author wording for the population, used in the title of PMID 22728005.

    Fields to search for renal impairment
  • TextAI

    "kidney impairment"[tiab]

    Variant of renal impairment.

    Fields to search for kidney impairment
  • TextAI

    "renal dysfunction"[tiab]

    Common author wording for reduced kidney function, used in PMID 22728005.

    Fields to search for renal dysfunction
  • TextAI

    "kidney dysfunction"[tiab]

    Variant of renal dysfunction.

    Fields to search for kidney dysfunction
  • TextAI

    "glomerular filtration rate"[tiab]

    CKD subgroups in trials are defined by GFR thresholds.

    Fields to search for glomerular filtration rate
  • TextAI

    eGFR[tiab]

    Abbreviation used to define CKD categories in trial analyses.

    Fields to search for eGFR
  • TextAI

    "creatinine clearance"[tiab]

    Alternative measure used to define renal impairment subgroups.

    Fields to search for creatinine clearance
  • TextAI

    "kidney function"[tiab]

    Captures analyses stratified by kidney function.

    Fields to search for kidney function
  • TextAI

    "renal function"[tiab]

    Captures analyses stratified by renal function.

    Fields to search for renal function
Suggested MeSH entry terms (2, off)
  • TextEntry term

    "Kidney Failure"[tiab]

    Narrower concept under the MeSH heading "Renal Insufficiency" (D051437)

    Fields to search for Kidney Failure
  • TextEntry term

    "Renal Failure"[tiab]

    Narrower concept "Kidney Failure" under the MeSH heading "Renal Insufficiency" (D051437)

    Fields to search for Renal Failure
Fields to search

Ischemic heart diseaseCondition

697,830 records · 16 of 16 terms on

  • MeSH valid: D017202AI

    "Myocardial Ischemia"[Mesh]

    Exploded heading covers coronary artery disease, coronary stenosis, angina and myocardial infarction, all part of ischemic heart disease.

  • TextAI

    "coronary artery disease*"[tiab]

    Main author term for the condition, used in PMID 24011740.

    Fields to search for coronary artery disease
  • TextAI

    "coronary disease*"[tiab]

    Entry-term variant.

    Fields to search for coronary disease
  • TextAI

    "coronary heart disease*"[tiab]

    Common synonym for coronary artery disease.

    Fields to search for coronary heart disease
  • TextAI

    "ischemic heart disease"[tiab]

    American spelling of the condition named in the question.

    Fields to search for ischemic heart disease
  • TextAI

    "ischaemic heart disease"[tiab]

    British spelling of the condition.

    Fields to search for ischaemic heart disease
  • TextAI

    "myocardial ischemia"[tiab]

    Entry-term synonym, American spelling.

    Fields to search for myocardial ischemia
  • TextAI

    "myocardial ischaemia"[tiab]

    British spelling.

    Fields to search for myocardial ischaemia
  • TextAI

    "myocardial infarction"[tiab]

    Trial populations with recent or prior infarction, as in OAT (PMID 22728005).

    Fields to search for myocardial infarction
  • TextAI

    angina[tiab]

    Symptomatic stable ischemic heart disease, as in PMID 24011740.

    Fields to search for angina
  • TextAI

    "acute coronary syndrome*"[tiab]

    Populations of invasive-versus-conservative trials.

    Fields to search for acute coronary syndrome
  • TextAI

    "coronary stenosis"[tiab]

    Anatomical finding targeted by revascularization.

    Fields to search for coronary stenosis
  • TextAI

    "coronary occlusion"[tiab]

    Occluded-artery populations, as in PMID 22728005.

    Fields to search for coronary occlusion
  • TextAI

    "multivessel coronary"[tiab]

    Multivessel disease populations of CABG and PCI trials.

    Fields to search for multivessel coronary
  • TextAI

    NSTEMI[tiab]

    Specific abbreviation for non-ST-elevation myocardial infarction.

    Fields to search for NSTEMI
  • TextAI

    STEMI[tiab]

    Specific abbreviation for ST-elevation myocardial infarction.

    Fields to search for STEMI
Fields to search

Coronary revascularization (PCI or CABG)Intervention

298,517 records · 16 of 16 terms on · 2 suggestions off

  • MeSH valid: D009204AI

    "Myocardial Revascularization"[Mesh]

    Exploded heading covers PCI, angioplasty and coronary artery bypass; indexed as major in PMID 22728005.

  • MeSH valid: D062645AI

    "Percutaneous Coronary Intervention"[Mesh]

    Heading for PCI, indexed in PMID 24011740.

  • MeSH valid: D001026AI

    "Coronary Artery Bypass"[Mesh]

    Heading for CABG, the surgical revascularization option.

  • TextAI

    revasculari*[tiab]

    Covers revascularization, revascularisation, revascularized and revascularised.

    Fields to search for revasculari
  • TextAI

    "percutaneous coronary intervention*"[tiab]

    Full name of PCI, singular and plural.

    Fields to search for percutaneous coronary intervention
  • TextAI

    PCI[tiab]

    Standard abbreviation for percutaneous coronary intervention.

    Fields to search for PCI
  • TextAI

    "coronary angioplasty"[tiab]

    Older wording for PCI.

    Fields to search for coronary angioplasty
  • TextAI

    "coronary stent*"[tiab]

    Stent implantation as the PCI technique.

    Fields to search for coronary stent
  • TextAI

    stenting[tiab]

    Common author wording for PCI with stents.

    Fields to search for stenting
  • TextAI

    "coronary artery bypass"[tiab]

    Full name of CABG.

    Fields to search for coronary artery bypass
  • TextAI

    CABG[tiab]

    Standard abbreviation for coronary artery bypass grafting.

    Fields to search for CABG
  • TextAI

    "bypass surgery"[tiab]

    Lay wording for CABG.

    Fields to search for bypass surgery
  • TextAI

    "invasive strateg*"[tiab]

    Trials such as ISCHEMIA-CKD compare an invasive strategy with conservative management.

    Fields to search for invasive strateg
  • TextAI

    "invasive management"[tiab]

    Variant wording of the invasive strategy.

    Fields to search for invasive management
  • TextAI

    "invasive treatment"[tiab]

    Variant wording of the invasive strategy.

    Fields to search for invasive treatment
  • TextAI

    "invasive approach"[tiab]

    Variant wording of the invasive strategy.

    Fields to search for invasive approach
Suggested MeSH entry terms (2, off)
  • TextEntry term

    "Internal Mammary Artery Implantation"[tiab]

    Narrower concept under the MeSH heading "Myocardial Revascularization" (D009204)

    Fields to search for Internal Mammary Artery Implantation
  • TextEntry term

    "Aortocoronary Bypass"[tiab]

    Synonym of the MeSH heading "Coronary Artery Bypass" (D001026)

    Fields to search for Aortocoronary Bypass
Fields to search

Randomized trialsStudy design

2,982,529 records · 7 of 7 terms on

  • MeSH valid: D016032AI

    "Randomized Controlled Trials as Topic"[Mesh]

    Heading for records about randomized trials, including secondary analyses.

  • MeSH valid: D002986AI

    "Clinical Trials as Topic"[Mesh]

    Broader trial heading for subgroup analyses not indexed as randomized.

  • MeSH valid: D011897AI

    "Random Allocation"[Mesh]

    Heading applied to records describing randomization.

  • TextAI

    random*[tiab]

    Covers randomized, randomised, randomly and randomization, used in PMID 24011740.

    Fields to search for random
  • TextAI

    trial*[tiab]

    Captures named trials and their secondary analyses, such as OAT (PMID 22728005) and COURAGE (PMID 24011740).

    Fields to search for trial
  • TextAI

    "post hoc"[tiab]

    CKD subgroup data often appear as post hoc analyses of trials.

    Fields to search for post hoc
  • TextAI

    "ISCHEMIA-CKD"[tiab]

    Key randomized trial of invasive versus conservative strategy in advanced CKD.

    Fields to search for ISCHEMIA-CKD
Fields to search

Death, cardiovascular events and kidney harmsOutcome

2,640,713 records · 10 of 10 terms on · 8 suggestions off

  • MeSH valid: D009026AI

    "Mortality"[Mesh]

    Heading for death outcomes.

  • MeSH valid: D058186AI

    "Acute Kidney Injury"[Mesh]

    Kidney harm after revascularization, including contrast nephropathy.

  • MeSH valid: D006435AI

    "Renal Dialysis"[Mesh]

    Progression to dialysis as a kidney harm.

  • TextAI

    mortality[tiab]

    Primary outcome of the review.

    Fields to search for mortality
  • TextAI

    death*[tiab]

    Death outcomes, singular and plural.

    Fields to search for death
  • TextAI

    "major adverse cardiac event*"[tiab]

    Composite cardiovascular outcome.

    Fields to search for major adverse cardiac event
  • TextAI

    MACE[tiab]

    Abbreviation of the composite cardiovascular outcome.

    Fields to search for MACE
  • TextAI

    "contrast induced nephropathy"[tiab]

    Kidney harm specific to angiography and PCI.

    Fields to search for contrast induced nephropathy
  • TextAI

    "acute kidney injury"[tiab]

    Kidney harm after revascularization.

    Fields to search for acute kidney injury
  • TextAI

    "kidney failure"[tiab]

    Progression to kidney failure as a kidney harm.

    Fields to search for kidney failure
Suggested MeSH entry terms (8, off)
  • TextEntry term

    "Case Fatality Rate"[tiab]

    Narrower concept under the MeSH heading "Mortality" (D009026)

    Fields to search for Case Fatality Rate
  • TextEntry term

    "CFR Case Fatality Rate"[tiab]

    Narrower concept "Case Fatality Rate" under the MeSH heading "Mortality" (D009026)

    Fields to search for CFR Case Fatality Rate
  • TextEntry term

    "Acute Renal Injury"[tiab]

    Synonym of the MeSH heading "Acute Kidney Injury" (D058186)

    Fields to search for Acute Renal Injury
  • TextEntry term

    "Acute Renal Failure"[tiab]

    Narrower concept "Kidney Failure, Acute" under the MeSH heading "Acute Kidney Injury" (D058186)

    Fields to search for Acute Renal Failure
  • TextEntry term

    "Acute Renal Insufficiency"[tiab]

    Narrower concept "Renal Insufficiency, Acute" under the MeSH heading "Acute Kidney Injury" (D058186)

    Fields to search for Acute Renal Insufficiency
  • TextEntry term

    "Acute Kidney Insufficiency"[tiab]

    Narrower concept "Renal Insufficiency, Acute" under the MeSH heading "Acute Kidney Injury" (D058186)

    Fields to search for Acute Kidney Insufficiency
  • TextEntry term

    "Extracorporeal Dialysis"[tiab]

    Narrower concept "Dialysis, Extracorporeal" under the MeSH heading "Renal Dialysis" (D006435)

    Fields to search for Extracorporeal Dialysis
  • TextEntry term

    Hemodialysis[tiab]

    Narrower concept under the MeSH heading "Renal Dialysis" (D006435)

    Fields to search for Hemodialysis
Fields to search

Limits

Publication types to exclude

Each one is checked against MeSH publication types before it is added.

  • Comment
  • Editorial
  • Letter
  • Case Reports
  • Preprint
  • Review

No changes.