Skip to content
PICO PortalSearch builder

From a question

Search terms included ‘transcatheter aortic valve replacement’ or ‘transcatheter aortic valve implantation’ or ‘TAVR’ or ‘TAVI’ and ‘transfemoral’ or ‘subclavian’ or ‘transsubclavian’ or ‘axillary’ or ‘transaxillary’ or ‘carotid’ or ‘transcarotid’ or ‘cava’ or ‘caval’ or ‘transcaval’.

DoneStarted Oct 28, 2026, 23:43 UTCFinished Oct 28, 2026, 23:44 UTC

Stages

  1. Finding the known studies(done)
  2. Drafting(done)
  3. Checking MeSH(done)
  4. Counting in PubMed(done)
  5. Checking known studies(done)
  6. Comparing with the reference(done)
  7. Run Search(done)
  8. Saving(done)
Run log (21)
  1. Finding the known studies: Finding 1 known study in PubMed
  2. Note: With fewer than 6 known studies matched to PubMed records (1 matched), all are kept for validation and none is shown to the model.
  3. Drafting: Drafting concepts and terms
  4. Checking MeSH: Checking every MeSH heading, Supplementary Concept and publication type against NLM
  5. Counting in PubMed: Running 12 lines on PubMed
  6. Line 2: 15,143 records
  7. Line 3: 24,706 records
  8. Line 1: 14,336 records
  9. Line 5: 26,126 records
  10. Line 6: 123,573 records
  11. Line 7: 276,535 records
  12. Line 10: 4,884,955 records
  13. Line 8: 323,407 records
  14. Line 9: 3,940 records
  15. Line 11: 2,992 records
  16. Line 4: 8,882 records
  17. Line 12: 919 records
  18. Checking known studies: Checking which known studies the final query finds
  19. Run Search: Fetching the first 20 records
  20. Saving: Saving the run
  21. Finished.

Final count (line 12)

919

Open in PubMed (opens in a new tab)
Query as run (1,169 characters)(((("Transcatheter Aortic Valve Replacement"[Mesh]) OR ("transcatheter aortic"[ti:~2]) OR ("transcatheter aortic valv*"[tiab] OR TAVR[tiab] OR TAVI*[tiab] OR "percutaneous aortic valve*"[tiab]) OR ("transcatheter aortic valve replacement"[ot] OR "transcatheter aortic valve implantation"[ot])) AND (("Femoral Artery"[Mesh] OR "Subclavian Artery"[Mesh] OR "Axillary Artery"[Mesh] OR "Carotid Arteries"[Mesh] OR "Vena Cava, Inferior"[Mesh]) OR (transfemoral[tiab] OR "trans-femoral"[tiab] OR "femoral access"[tiab] OR "femoral approach"[tiab] OR subclavian[tiab] OR transsubclavian[tiab] OR "trans-subclavian"[tiab] OR axillary[tiab] OR transaxillary[tiab] OR "trans-axillary"[tiab] OR carotid[tiab] OR transcarotid[tiab] OR "trans-carotid"[tiab] OR cava[tiab] OR caval[tiab] OR transcaval[tiab] OR "trans-caval"[tiab] OR "alternative access"[tiab] OR "non-femoral"[tiab] OR nonfemoral[tiab] OR "non-transfemoral"[tiab] OR "access route*"[tiab]))) NOT ("Comment"[Publication Type] OR "Editorial"[Publication Type] OR "Letter"[Publication Type] OR "Case Reports"[Publication Type] OR "Preprint"[Publication Type])) AND english[la] AND ("2022/07/01"[dp] : "2027/12/31"[dp])

Known studies

1 of 1 found

95% CI 3%–100%

Only studies the model never saw are counted. Finding known studies does not prove the search is complete.

Each study (1)
  • Found: 10.1016/j.jjcc.2023.04.015PMID 37116649 · held back for validation

Reference strategy

No reference strategy was given.

Search lines

Vocabulary terms are marked ✓︎ valid, ↪︎ mapped to the preferred heading, ✗︎ not found, ⚠︎ not checked.
Numbered search lines with their PubMed counts
No.SearchResults
1

Transcatheter aortic valve replacement/implantation

"Transcatheter Aortic Valve Replacement"[Mesh] (MeSH heading valid: D065467)		14,336
2

Transcatheter aortic valve replacement/implantation

"transcatheter aortic"[ti:~2]		15,143
3

Transcatheter aortic valve replacement/implantation

"transcatheter aortic valv*"[tiab] OR TAVR[tiab] OR TAVI*[tiab] OR "percutaneous aortic valve*"[tiab]		24,706
4

Transcatheter aortic valve replacement/implantation

"transcatheter aortic valve replacement"[ot] OR "transcatheter aortic valve implantation"[ot]		8,882
5

Transcatheter aortic valve replacement/implantation · block

1 OR 2 OR 3 OR 4		26,126
6

Vascular access route

"Femoral Artery"[Mesh] (MeSH heading valid: D005263) OR "Subclavian Artery"[Mesh] (MeSH heading valid: D013348) OR "Axillary Artery"[Mesh] (MeSH heading valid: D001366) OR "Carotid Arteries"[Mesh] (MeSH heading valid: D002339) OR "Vena Cava, Inferior"[Mesh] (MeSH heading valid: D014682)		123,573
7

Vascular access route

transfemoral[tiab] OR "trans-femoral"[tiab] OR "femoral access"[tiab] OR "femoral approach"[tiab] OR subclavian[tiab] OR transsubclavian[tiab] OR "trans-subclavian"[tiab] OR axillary[tiab] OR transaxillary[tiab] OR "trans-axillary"[tiab] OR carotid[tiab] OR transcarotid[tiab] OR "trans-carotid"[tiab] OR cava[tiab] OR caval[tiab] OR transcaval[tiab] OR "trans-caval"[tiab] OR "alternative access"[tiab] OR "non-femoral"[tiab] OR nonfemoral[tiab] OR "non-transfemoral"[tiab] OR "access route*"[tiab]		276,535
8

Vascular access route · block

6 OR 7		323,407
9

combined

5 AND 8		3,940
10

excluded

"Comment"[Publication Type] (publication type valid: D016420) OR "Editorial"[Publication Type] (publication type valid: D016421) OR "Letter"[Publication Type] (publication type valid: D016422) OR "Case Reports"[Publication Type] (publication type valid: D002363) OR "Preprint"[Publication Type] (publication type valid: D000076942)		4,884,955
11

exclusions removed

9 NOT 10		2,992
12Final

limits

11 AND english[la] AND ("2022/07/01"[dp] : "2027/12/31"[dp])		919

Issues

0 errors, 2 warnings, 1 notes
  • Warning: Language limit (english): it can remove relevant studies; report and justify it.
  • Warning: Publication types excluded with NOT (Comment, Editorial, Letter, Case Reports, Preprint): report and justify the exclusion.
  • Note: With fewer than 6 known studies matched to PubMed records (1 matched), all are kept for validation and none is shown to the model.

First records

The first 20 of the final line's records, as PubMed sorts them.
  1. Early and Long-Term Results of 101 Consecutive Patients After Transcarotid Transcatheter Aortic Valve Implantation. (PubMed, opens in a new tab)

    Hudziak D, Gruz-Kwapisz M, Parma R et al. · Journal of clinical medicine · 2026 · PMID 42941432

  2. Rapidly Reversible Monitored Anesthesia Care with Remimazolam and Flumazenil Reversal for Transcatheter Aortic Valve Replacement: A Randomized Controlled Trial. (PubMed, opens in a new tab)

    Kitaura A, Mino T, Yoshino Y et al. · Journal of clinical medicine · 2026 · PMID 42941394

  3. Clinical Outcomes of Concurrent Impella-Assisted High-Risk PCI and TAVR in Patients With Complex Coronary Artery Disease and Severe Aortic Stenosis. (PubMed, opens in a new tab)

    Rivera FB, Ingraham B, Di Santo P et al. · Journal of the Society for Cardiovascular Angiography & Interventions · 2026 · PMID 42936101

  4. Lifetime Management of Aortic Stenosis: Expert Review of Evidence and Consensus Guidelines. (PubMed, opens in a new tab)

    Centofanti P, Rinaldi M, Di Eusanio M et al. · The Annals of thoracic surgery · 2026 · PMID 42933524

  5. A semi-rapid deployment workflow to reduce device time in Evolut FX self-expanding transcatheter aortic valve implantation. (PubMed, opens in a new tab)

    Doi S, Iwata H, Sato E et al. · AsiaIntervention · 2026 · PMID 42924251

  6. Dedicated versus off-label transcatheter devices for pure native aortic regurgitation via transfemoral access: a meta-analysis of contemporary outcomes. (PubMed, opens in a new tab)

    Hon JJ, Egrilmezer A, Hon JKF · AsiaIntervention · 2026 · PMID 42923763

  7. Temporal changes in dilated ascending aorta after transfemoral TAVR: a comparative analysis of bicuspid and tricuspid aortic valves. (PubMed, opens in a new tab)

    Xu Q, Xu Z, Dai X et al. · Frontiers in cardiovascular medicine · 2026 · PMID 42920634

  8. Early and Mid-Term Mortality After Transcatheter Aortic Valve Implantation: Five-Year Experience from the KOSUTAVI Study. (PubMed, opens in a new tab)

    Zehir R, Alizade E, Usalp S et al. · Anatolian journal of cardiology · 2026 · PMID 42904374

  9. Ultrasound-Guided versus Fluoroscopy-Guided Femoral Access for Structural Heart Procedures: Outcomes From Transcatheter Aortic Valve Implantation and Left Atrial Appendage Closure. (PubMed, opens in a new tab)

    Kıvrak A, Sezer C, Canpolat U et al. · Anatolian journal of cardiology · 2026 · PMID 42897923

  10. Transcarotid Access for Transcatheter Aortic Valve Replacement With the Evolut Self-Expanding Valve: Outcomes from a Real-World Registry. (PubMed, opens in a new tab)

    Allen KB, Huded C, Cohen DJ et al. · The Annals of thoracic surgery · 2026 · PMID 42887713

  11. Short-Term Complications of Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis (PROLONG-TAVR). (PubMed, opens in a new tab)

    Castillo-Perez M, León-Gutiérrez H, Jerjes-Sánchez C et al. · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026 · PMID 42876001

  12. Short-frame, self-expanding, fully recapturable transcatheter aortic valve replacement device in pure aortic regurgitation: Procedural performance and 30-day outcomes. (PubMed, opens in a new tab)

    Yan H, Li Y, Wan W et al. · Cardiovascular revascularization medicine : including molecular interventions · 2026 · PMID 42875325

  13. Surgery that looks like transcatheter aortic valve implantation: the transaxillary concept for minimally invasive aortic valve replacement in 1,848 consecutive patients. (PubMed, opens in a new tab)

    Arzt S, Alexiou K, Taghizadeh-Waghefi A et al. · Annals of cardiothoracic surgery · 2026 · PMID 42870852

  14. Enhanced recovery after surgery turnkey order set for periprocedural care of the patient undergoing transcatheter aortic valve replacement. (PubMed, opens in a new tab)

    Engelman DT, Ailawadi G, Russo MJ et al. · JTCVS structural and endovascular · 2026 · PMID 42857632

  15. Age-Related Excessive Tortuosity of the Right Brachiocephalic Artery in Patients Being Evaluated for Transcatheter Aortic Valve Replacement (TAVR): Potential to Affect Alternate Access. (PubMed, opens in a new tab)

    Girgis K, Gupta PK, Retcho D et al. · Cureus · 2026 · PMID 42825221

  16. Peripheral vessel tortuosity index and prognosis in patients undergoing transcatheter aortic valve implantation. (PubMed, opens in a new tab)

    Alvarez-Covarrubias HA, Jurisic M, Seguchi M et al. · Clinical research in cardiology : official journal of the German Cardiac Society · 2026 · PMID 42821072

  17. SAFE-SEAL: a bail-out technique for percutaneous femoral closure after failed hybrid closure. (PubMed, opens in a new tab)

    Angelillis M, Misuraca L, Calabria P et al. · The Journal of invasive cardiology · 2026 · PMID 42814485

  18. Transfemoral TAVR With a 35-mm Myval Valve in an Extremely Large Aortic Annulus Using Intentional Undersizing. (PubMed, opens in a new tab)

    Magyari B, Kittka B, Goják I et al. · JACC. Cardiovascular interventions · 2026 · PMID 42805726

  19. Remimazolam Versus Dexmedetomidine for Monitored Anesthesia Care in Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation: A Randomized Clinical Trial. (PubMed, opens in a new tab)

    Hyung SW, Choi M, Chung MY et al. · Journal of clinical medicine · 2026 · PMID 42795954

  20. Enabling Transfemoral TAVI Through a Hostile Abdominal Aortic Anatomy and a Migrated Mesenteric Stent Fragment: Review of the Literature and a Case Presentation. (PubMed, opens in a new tab)

    Parasca CA, Radulescu CI, Platon P et al. · Life (Basel, Switzerland) · 2026 · PMID 42795392

Export

Strategy (.txt)PMIDs (.txt)MEDLINE (.txt)Provenance (.json)

The strategy file has the numbered lines with counts, the search date and the AI-use statement. PMIDs and MEDLINE are fetched from PubMed when you download, so they reflect PubMed today.

Checking PubMed for the current list of PMIDs…

Objective and notes from the draft

To identify studies of transcatheter aortic valve replacement or implantation (TAVR/TAVI) that report on the vascular access route used: transfemoral, or the alternative routes subclavian/axillary, carotid, or transcaval.

  • The question lists search terms rather than a formal question; I assumed the review concerns TAVR access routes (transfemoral and the alternative subclavian/axillary, carotid and transcaval routes) and combined the two term groups with AND.
  • The bare words carotid, axillary, subclavian, cava and caval were kept because the searcher named them; carotid in particular will also find TAVR studies that only mention carotid disease or stroke, so expect some screening noise.
  • I added umbrella phrases (alternative access, non-femoral, non-transfemoral, access route*) for sensitivity; remove them if only the named routes are wanted.
  • Transapical and direct aortic (transaortic) access were not named by the searcher and were left out; add transapical and transaortic as text words if those routes are in scope.
  • The access-artery MeSH headings are not restricted to major topic because they are usually assigned as minor headings on TAVR records.

Edit the strategy

Changes are not searched until you recount. Each recount is saved as a new version.

Transcatheter aortic valve replacement/implantationIntervention

26,126 records · 8 of 8 terms on

  • MeSH valid: D065467AI

    "Transcatheter Aortic Valve Replacement"[Mesh]

    The specific heading for TAVR/TAVI; not restricted to major topic so that access-route studies indexed with it as a minor heading are kept.

  • TextAI

    "transcatheter aortic valv*"[tiab]

    Covers transcatheter aortic valve replacement, implantation, valves and valve-in-valve in one truncated phrase.

    Fields to search for transcatheter aortic valv
  • TextAI

    "transcatheter aortic valve replacement"[ot]

    Author keyword form of the searcher's first term.

    Fields to search for transcatheter aortic valve replacement
  • TextAI

    "transcatheter aortic valve implantation"[ot]

    Author keyword form of the searcher's second term.

    Fields to search for transcatheter aortic valve implantation
  • TextAI

    TAVR[tiab]

    Standard abbreviation named by the searcher.

    Fields to search for TAVR
  • TextAI

    TAVI*[tiab]

    Standard abbreviation named by the searcher; truncation also finds TAVIs.

    Fields to search for TAVI
  • TextAI

    "transcatheter aortic"[ti:~2]

    Catches title wordings such as transcatheter aortic bioprosthesis or transcatheter aortic prosthesis.

    Fields to search for transcatheter aortic
  • TextAI

    "percutaneous aortic valve*"[tiab]

    Older synonym for TAVR still used by some authors.

    Fields to search for percutaneous aortic valve
Fields to search

Vascular access routeExposure

323,407 records · 27 of 27 terms on · 1 suggestion off

  • MeSH valid: D005263AI

    "Femoral Artery"[Mesh]

    Indexing for transfemoral access.

  • MeSH valid: D013348AI

    "Subclavian Artery"[Mesh]

    Indexing for subclavian/transsubclavian access.

  • MeSH valid: D001366AI

    "Axillary Artery"[Mesh]

    Indexing for axillary/transaxillary access.

  • MeSH valid: D002339AI

    "Carotid Arteries"[Mesh]

    Indexing for carotid/transcarotid access; exploded to include the common carotid artery.

  • MeSH valid: D014682AI

    "Vena Cava, Inferior"[Mesh]

    Indexing for caval/transcaval access.

  • TextAI

    transfemoral[tiab]

    Searcher's term for the standard femoral route.

    Fields to search for transfemoral
  • TextAI

    "trans-femoral"[tiab]

    Hyphenated spelling, read by PubMed as a separate phrase from transfemoral.

    Fields to search for trans-femoral
  • TextAI

    "femoral access"[tiab]

    Common wording for the transfemoral route.

    Fields to search for femoral access
  • TextAI

    "femoral approach"[tiab]

    Alternative wording for the transfemoral route.

    Fields to search for femoral approach
  • TextAI

    subclavian[tiab]

    Searcher's term for subclavian access.

    Fields to search for subclavian
  • TextAI

    transsubclavian[tiab]

    Joined spelling named by the searcher.

    Fields to search for transsubclavian
  • TextAI

    "trans-subclavian"[tiab]

    Hyphenated spelling, read as the phrase trans subclavian.

    Fields to search for trans-subclavian
  • TextAI

    axillary[tiab]

    Searcher's term for axillary access.

    Fields to search for axillary
  • TextAI

    transaxillary[tiab]

    Joined spelling named by the searcher.

    Fields to search for transaxillary
  • TextAI

    "trans-axillary"[tiab]

    Hyphenated spelling, read as the phrase trans axillary.

    Fields to search for trans-axillary
  • TextAI

    carotid[tiab]

    Searcher's term for carotid access.

    Fields to search for carotid
  • TextAI

    transcarotid[tiab]

    Joined spelling named by the searcher.

    Fields to search for transcarotid
  • TextAI

    "trans-carotid"[tiab]

    Hyphenated spelling, read as the phrase trans carotid.

    Fields to search for trans-carotid
  • TextAI

    cava[tiab]

    Searcher's term, capturing vena cava access.

    Fields to search for cava
  • TextAI

    caval[tiab]

    Searcher's term for caval access.

    Fields to search for caval
  • TextAI

    transcaval[tiab]

    Joined spelling named by the searcher.

    Fields to search for transcaval
  • TextAI

    "trans-caval"[tiab]

    Hyphenated spelling, read as the phrase trans caval.

    Fields to search for trans-caval
  • TextAI

    "alternative access"[tiab]

    Umbrella phrase for non-femoral routes, used in comparisons that may not name each route in title or abstract.

    Fields to search for alternative access
  • TextAI

    "non-femoral"[tiab]

    Umbrella term for alternative access routes.

    Fields to search for non-femoral
  • TextAI

    nonfemoral[tiab]

    Joined spelling of non-femoral.

    Fields to search for nonfemoral
  • TextAI

    "non-transfemoral"[tiab]

    Umbrella term for alternative access routes.

    Fields to search for non-transfemoral
  • TextAI

    "access route*"[tiab]

    Generic phrase for studies comparing TAVR access routes.

    Fields to search for access route
Suggested MeSH entry terms (1, off)
  • TextEntry term

    "Common Femoral Artery"[tiab]

    Narrower concept under the MeSH heading "Femoral Artery" (D005263)

    Fields to search for Common Femoral Artery
Fields to search

Limits

Publication types to exclude

Each one is checked against MeSH publication types before it is added.

  • Comment
  • Editorial
  • Letter
  • Case Reports
  • Preprint

No changes.